Lee Carsley has handed call-ups to Angel Gomes, Tino Livramento, Morgan Gibbs-White and Noni Madueke in his first squad since being named England interim manager.
Lille winger Gomes, Newcastle defender Livramento, Nottingham Forest midfielder Gibbs-White and Chelsea winger Madueke all played for Carsley during his time as England U21 manager.
England take on the Republic of Ireland in Dublin on 7 September (17:00 BST) and Finland at Wembley on 10 September (19:45) in the Nations League.
Carsley was appointed to the role following Gareth Southgate’s resignation after Euro 2024.
Manchester City playmaker Jack Grealish, who was cut from England’s preliminary Euro 2024 squad, has been recalled as well as Manchester United defender Harry Maguire.
Gomes, 23, helped England U21s win the European Championship in 2023 under Carsley.
The Manchester United academy graduate left Old Trafford for Lille in 2020, having made five appearances for the Red Devils. In 2017 he became the club’s youngest player since Duncan Edwards in the 1950s when he made his first-team debut at the age of 16.
He was also the first player born in the 2000s to appear in the Premier League.
Gomes was taken to hospital on 17 August after suffering a head injury in a Ligue 1 fixture against Reims. He later said he was “all good” after receiving treatment.
Brentford striker Ivan Toney, Manchester City defender Kyle Walker and Arsenal goalkeeper Aaron Ramsdale, who were all in the Euros squad, have been left out of the 26-man squad.
Arsenal defender Ben White, who earned the last of his four caps in March 2022, is also not in the squad after once again making himself unavailable for selection.
Manchester United defender Luke Shaw and Real Madrid midfielder Jude Bellingham both miss out through injury, while United forward Marcus Rashford is not included.
Newcastle United full-back Kieran Trippier, who played 54 times under Southgate, announced his retirement from international football on Thursday.
Full England squad
Goalkeepers: Dean Henderson (Crystal Palace), Jordan Pickford (Everton), Nick Pope (Newcastle United)
Defenders: Marc Guehi (Crystal Palace), Ezri Konsa (Aston Villa), John Stones (Manchester City), Trent Alexander-Arnold (Liverpool), Levi Colwill (Chelsea), Rico Lewis (Manchester City), Tino Livramento (Newcastle), Harry Maguire (Manchester United)
Midfielders: Conor Gallagher (Atletico Madrid), Kobbie Mainoo (Manchester United), Declan Rice (Arsenal), Cole Palmer (Chelsea), Morgan Gibbs-White (Nottingham Forest), Angel Gomes (Lille), Phil Foden (Manchester City)
Forwards: Jarrod Bowen (West Ham), Eberechi Eze (Crystal Palace), Jack Grealish (Manchester City), Anthony Gordon (Newcastle United), Harry Kane (Bayern Munich), Noni Madueke (Chelsea) Bukayo Saka (Arsenal), Ollie Watkins (Aston Villa).